skip to main content

Winston-Salem directions, for your exploring pleasure

401 North Main Street,
Winston-Salem, NC 27101
(336) 724-1009

A Winston-Salem Map For You

With its Art Deco architecture, Kimpton Cardinal Hotel stands apart in the Winston-Salem skyline, so you shouldn’t have any trouble finding us. Once you do, there’s plenty to explore on foot throughout our vibrant downtown neighborhood, from indoor-outdoor restaurants on Fourth Street to the Arts District centered around Sixth and Trade streets to the coffeehouses and bars of Burke Street. Don’t miss historic Old Salem Museums & Gardens and Reynolda House Museum of Art — the estate and 60-room “bungalow” built by tobacco tycoon R.J. Reynolds and his wife, Katharine. Farther afield, you’ll find Yadkin Valley wine country, producing varieties from Aleatico to Zinfandel. For a mid-size city, Winston-Salem has a surprising variety of ways to stir your imagination.

From The West

  • Take I-40 E towards Winston-Salem/Greensboro
  • Take 40BUS E/US-421 S towards Downtown Winston-Salem
  • Exit towards Peters Creek Parkway
  • Turn left onto Second Street
  • Turn left onto Main Street
  • Kimpton Cardinal Hotel is 2 blocks down on your right

From The East (PTI Airport, GSO and RDU Airport)

  • Take I-40 W towards Winston-Salem/Greensboro
  • Merge right onto 40BUS W/US-421N
  • Exit U.S. 52 South
  • Exit onto Research Parkway and continue west
  • At the traffic circle, take the 3rd exit onto E 3rd St
  • Turn right onto Main St
  • Kimpton Cardinal is 1 block down on your right

From The South (CLT airport)

  • Take I-85N toward Greensboro
  • Right at fork to continue on I-85BUS N/US-52N
  • Keep left to continue on US-52N
  • Take exit towards S Research Pkwy
  • Keep left at the fork and merge onto S Research Pkwy
  • At the traffic circle, take the 3rd exit onto E 3rd St
  • Turn right onto Main St
  • Kimpton Cardinal is 1 block down on your right

From The North

  • Take I-85 S towards Durham
  • Merge onto I-40 W towards Greensboro/Winston Salem
  • Merge right onto 40BUS W/US-421 N
  • Exit U.S 52 South
  • Exit onto Research Parkway and continue west
  • At the traffic circle, take the 3rd exit onto E 3rd St
  • Turn right onto Main St
  • Kimpton Cardinal is 1 block down on your right

Walk or Ride to Nearby Attractions from Kimpton Cardinal Hotel