Kimpton Karma + IHG® Rewards Club

Winston-Salem directions, for your exploring pleasure

401 North Main Street,
Winston-Salem, NC 27101
(336) 724-1009

A Winston-Salem Map For You

With its Art Deco architecture, Kimpton Cardinal Hotel stands apart in the Winston-Salem skyline, so you shouldn’t have any trouble finding us. Once you do, there’s plenty to explore on foot throughout our vibrant downtown neighborhood, from indoor-outdoor restaurants on Fourth Street to the Arts District centered around Sixth and Trade streets to the coffeehouses and bars of Burke Street. Farther afield, don’t miss historic Old Salem Museums & Gardens and Reynolda House Museum of Art — the estate and 60-room “bungalow” built by tobacco tycoon R.J. Reynolds and his wife, Katharine. Farther afield, you’ll find Yadkin Valley wine country, producing varieties from Aleatico to Zinfandel. For a mid-size city, Winston-Salem has a surprising variety of ways to stir your imagination.

From The West

  • Take I-40 E towards Winston-Salem/Greensboro
  • Take 40BUS E/US-421 S towards Downtown Winston-Salem
  • Exit towards Peters Creek Parkway
  • Turn left onto Second Street
  • Turn left onto Main Street
  • Kimpton Cardinal Hotel is 2 blocks down on your right

From The East (PTI Airport, GSO and RDU Airport)

  • Take I-40 W towards Winston-Salem/Greensboro
  • Merge right onto 40BUS W/US-421N
  • Exit U.S. 52 South
  • Exit onto Research Parkway and continue west
  • At the traffic circle, take the 3rd exit onto E 3rd St
  • Turn right onto Main St
  • Kimpton Cardinal is 1 block down on your right

From The South (CLT airport)

  • Take I-85N toward Greensboro
  • Right at fork to continue on I-85BUS N/US-52N
  • Keep left to continue on US-52N
  • Take exit towards S Research Pkwy
  • Keep left at the fork and merge onto S Research Pkwy
  • At the traffic circle, take the 3rd exit onto E 3rd St
  • Turn right onto Main St
  • Kimpton Cardinal is 1 block down on your right

From The North

  • Take I-85 S towards Durham
  • Merge onto I-40 W towards Greensboro/Winston Salem
  • Merge right onto 40BUS W/US-421 N
  • Exit U.S 52 South
  • Exit onto Research Parkway and continue west
  • At the traffic circle, take the 3rd exit onto E 3rd St
  • Turn right onto Main St
  • Kimpton Cardinal is 1 block down on your right

Business 40 Detour Route Exits

Walk or Ride to Nearby Attractions from Kimpton Cardinal Hotel